Penn Center East At A Glance:
• 400 Penn Center Blvd., Pittsburgh, PA 15235
• Prominent visibility along William Penn Highway (Rt. 22)
• Easy access to I-376 and Pennsylvania Turnpike
• 10 miles east of Downtown Pittsburgh
• Wilkins Township (Monroeville Area)
• Allegheny County

From the North:

I-279 South to I-579 South via Exit 8 (Veterans Bridge)
I-376 East/Oakland/Monroeville Exit
Straight onto the Blvd. of the Allies
Merge onto I-376 East/U.S. 22 toward Monroeville
After approximately 8 miles, take U.S. 22 to Exit 10B (Monroeville)
Continue straight onto William Penn Hwy/U.S. 22
Follow for approximately 1 mile; turn right onto Penn Center Blvd.

From the South:

I-279 North/U.S. 22/30 East
Merge onto I-376 East/U.S. 22 East via Exit 6A (Monroeville)
After approximately 10 miles, take U.S. 22 East to Exit 10B (Monroeville)
Continue straight onto William Penn Hwy/U.S. 22
Follow for approximately 1 mile; turn right onto Penn Center Blvd.  

From the East (PA Turnpike):

From PA Turnpike (I-76) take Exit 57(Pittsburgh), toward Pittsburgh/Monroeville;
Take U.S. 22 Business on the left toward Monroeville;
Merge onto U.S. 22/William Penn Highway;
Travel three miles and turn left onto Penn Center Boulevard.  

From the Airport:

Take PA-60 South toward Pittsburgh/I-79/Pittsburgh
Continue on U.S. 22/30 East
Take Exit 6A toward Monroeville onto I-376 East/U.S. 22
Follow for approximately 10 miles to Exit 10B (Monroeville)
Continue straight onto William Penn Hwy/U.S. 22
Follow for approximately 1 mile; turn right onto Penn Center Blvd.